In a surprising—and irony-rich—byproduct of the Afghan war, the Pentagon finds itself dependent on a scientific research arm of the Iranian government to treat bites by Oxus cobras, Haly's pit vipers and other snakes peculiar to the battlefields of southwest Asia.

Despite U.S.-led international sanctions designed to paralyze Iran's trade with the outside world, the Defense Department buys the drugs through a middleman, with orders totaling 115 vials at $310 apiece since January 2011.

Medical guidance issued by U.S. Central Command says drugs made by Iran's Razi Vaccine & Serum Research Institute "should be the first line of antivenin therapy" because they counter venoms of the most-common Afghan snakes, said a U.S. officer who has read it.

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For their part, the Iranians say they are willing to sell Razi drugs to anyone. "We make this to save lives, and it doesn't matter if the person is Iranian or Afghan or American," said Hadi Zareh, lead researcher in Razi's antivenin department. "We are happy to hear we have saved a person's life, even an American soldier."

Prompted by questions from The Wall Street Journal, Pentagon lawyers are investigating whether the purchases violate sanctions rules and require a waiver from the U.S. Treasury Department. "We are working with the Department of Defense to confirm the details of these purchases to ensure compliance" with sanctions regulations, a Treasury spokesman said.

Mr. Zareh said the U.S.-led sanctions campaign, intended to discourage Iran from pursuing nuclear weapons, has had the side effect of making it harder for Razi to produce the very drugs the American military is purchasing. The institute, he said in an interview, is finding it "very difficult to buy chemical products for the laboratories and some of the equipment that we need. Prices have also increased because of sanctions."

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"The Iranian antivenin is the best, and our guys deserve the best," said Col. Rob Russell, the hospital's medical director.

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