[morte-vivante]

Oorspronkelijk geplaatst door geertvdb

En dan heb ik het nog niet gehad over wat ge schrijft over kankerpatiënten. gewoon oerdom.

Cannabis heeft zijn plaats binnen een kankerbehandeling omdat het de potentiële nevenwerkingen van die behandeling kan tegengaan. En Cannabis heeft zijn plaats binnen een palliatief plan, mocht de behandeling niet aanslaan.

Dronabinol wordt gebruikt als anti-emeticum en stimuleert de eetlust, en wordt oa gecommercialiseerd door Solvay. Klinische studies tonen aan dat het geneesmiddel ook het gewichtsverlies dat gepaard gaat met kanker tegengaat.

Nabilone, een synthetisch cannabinoid, wordt gebruikt voor gelijkaardige symptomen, en voor de behandeling van neuropathische pijn.

enkele links:
Effect van cannabis op de nutritionele status van longkankerpatienten:

Our findings support that treatment with nabilone in patients diagnosed with anorexia increases energy consumption, specifically carbohydrates, and improves functional scales of quality of life, pain, and insomnia.

This study exposes the potential improvement effect in quality of life in lung cancer patients undergoing either chemotherapy or targeted therapy, for which it is known that nutritional status greatly affects efficacy and toxicity profile [9, 32]. Moreover, the side effects of cannabis are generally tolerable and short lived [16]. One of the most expected side effects from nabilone is somnolence, which in the present study was significantly beneficial to balance the insomnia reported in the experimental group.

https://rd.springer.com/article/10.1...520-018-4154-9

Palliative effects of phytocannabinoids, such as on pain, mood, appetite, and radiation- or chemotherapy-induced nausea and vomiting, have been studied in cancer patients since the early 1970s. The striking benefit of these substances is their multitarget action and compatibility with many eventually needed comedications, as well as their impressive safety margin. Although dosages must be adapted to individual needs, multiple therapeutic effects can be achieved simultaneously with only one product, such as reducing pain, spasticity, depression and anxiety; improving mood and sleep; increasing appetite and weight; etc.

https://academic.oup.com/nop/article/4/3/151/2918616

en preklinische studies tonen aan dat het tijd wordt dat er klinische studies worden opgezet om na te gaan wat het potentiele effect is van cannabis zelf op verschillende vormen van kanker:

From a pharmaceutical point of view, CBD represents at the moment the most promising compound present in C. sativa. Although this component is well-known mainly for its antioxidant and anti-inflammatory activities, a number of researches pointed out its ability to interfere with cell proliferation apoptosis and cancer growth. If we consider also that cancer biology and inflammation share several common pathways in some stages of their biological processes, CBD might be a potential important tool in the control of cancer spread and growth.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304621/

One important factor that further argues for the use of cannabinoid-based drugs in cancer therapy may lie in their synergistic action on the efficacy of currently used chemotherapeutic drugs. Particularly, ?9-THC and CBD were found to synergistically act on anticarcinogenic properties of bortezomib (Morelli et al., 2014), carfilzomib (Nabissi et al., 2016), carmustine (Nabissi et al., 2013), cisplatin (Deng et al., 2017), cytarabine (Liu W. M. et al., 2008), doxorubicin (Liu W. M. et al., 2008; Nabissi et al., 2013; Elbaz et al., 2016), mitoxantrone (Holland et al., 2007), temozolomide (Torres et al., 2011; Nabissi et al., 2013; López-Valero et al., 2018), and vinca alkaloids (Holland et al., 2006; Liu W. M. et al., 2008).

Taken together, cannabinoids and compounds affecting the endocannabinoid system may complement the range of currently used chemotherapeutic agents as a pharmacotherapeutic option for cancer treatment with broadly diversified mechanisms.

https://www.frontiersin.org/articles...00430/full#B69

en case reports zijn veelbelovend:

Clinical responses were seen in 92% of the 119 cases with solid tumours including a reduction in circulating tumour cells in many cases and in other cases, a reduction in tumour size, as shown by repeat scans. No side-effects of any kind were observed when using pharmaceutical grade synthetic cannabidiol.

http://ar.iiarjournals.org/content/38/10/5831.full

maar nog wel een lange weg te gaan, en we hebben heel wat tijd verloren door de classificatie van cannabis

het enige dat dus eigenlijk oerdom is, is uw reactie