De wuhan mutanten komen er aan!

[Karel Martel B]

https://chrismasterjohnphd.com/covid...than-east-asia

According to computer modeling conducted by the researchers who wrote the new paper, the D614G mutation has altered the spike protein so that it can now get cleaved in a second spot by a different enzyme known as elastase.

If correct, this offers several big opportunities for the virus to spread faster:

Now it has two ways to get cleaved. If there isn't enough TMPRSS2 in any given instance, it will have elastase as a second option.

While TMPRSS2 is bound to the cell membrane, elastase is freely circulating in the extracellular fluid. There may be instances where TMPRSS2 and ACE2 are both available, but not located closely enough to initiate a fusion event. Under those circumstances the free-floating elastase should have better access to cleave the spike protein and initiate fusion.

The spike protein may get cleaved in two spots instead of one. It is possible that a larger number of smaller pieces of the spike protein could have a “decoy” effect by distracting the immune system to focus on the broken pieces of the spike protein rather than the part of the spike protein busy infecting the human cells.

conclusie:

Studies and arguments about whether one country was hit harder or recovered faster because of its policies need to take into account the different genetics of their populations and how it has impacted the spread of the G mutation.

[patrickve]

Oeps. 't is begonnen.